Pulmonary Embolism – Diagnosis and Exclusion

Initiation of Diagnostic Testing

  • Requires at least one symptom referable to the chest
  • Assess Vitals – look for tachycardia, hypoxia (<95% on RA or a new O2 requirement), tachypnea
  • Assess ECG for signs of pulmonary hypertension (Tachycardia, S1Q3T3, TWI in anterior leads, incomplete RBBB)

Note: Low clinical suspicion + PERC negative predicts an outcome rate of PE <1%

PERC Rule

If PERC negative, there is <2% chance of a PE

D-Dimer Testing

  • Indicated for patients with low-pretest probability; Wells score: 2-4; sRGS 2-4
  • D-dimer will remain high for up to 72 hours after symptom onset
  • Age-adjusted Dimer formula: Age *10 ng/mL
  • All patients with a positive dimer should undergo diagnostic testing to investigate the presence of a clot

Gestalt

  • Gestalt or implicit reasoning has similar diagnostic performance characteristics and inter-observer reliability as the Well’s score or RGS

Diagnostic testing Map

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